Spyre TherapeuticsUnited States

IT Support Analyst

Spyre Therapeutics is a biotechnology company that aims to create next-generation inflammatory bowel disease (IBD) and other immune-mediated disease products by combining best-in-class antibody engineering, rational therapeutic combinations, and precision medicine approaches.

Spyre Therapeutics is a biotechnology company that aims to create next-generation inflammatory bowel disease (IBD) and other immune-mediated disease products by combining best-in-class antibody engineering, rational therapeutic combinations, and precision medicine approaches. Spyre’s pipeline includes extended half-life antibodies targeting α4β7, TL1A, and IL-23.

Role Summary

As an IT Support Analyst, you will provide comprehensive technical support to our fully remote workforce, ensuring a seamless and secure user experience across systems and devices. Leveraging your proven experience in IT support, you’ll resolve a wide range of technical issues while delivering an exceptional level of customer service that fosters user satisfaction and trust.

In addition to handling support requests, you will contribute to endpoint security by assisting with patch management, device compliance monitoring, and implementation of standard security protocols. You’ll play a critical role in bridging IT operations and user support balancing hands-on troubleshooting with proactive measures to ensure systems remain secure, stable, and aligned with company policies. This role offers the opportunity to grow into broader infrastructure or security responsibilities while serving as a dependable point of contact for our internal teams.

Key Responsibilities

  • Deliver High-Quality IT Support: Act as a reliable support resource for employees, providing timely and professional resolution to hardware, software, and connectivity issues across macOS and Windows environments. Ensure a smooth experience across tools like Office 365, Zoom, SharePoint, and collaboration platforms.
  • Provide Exceptional Customer Service: Maintain a user-first mindset by actively listening, communicating clearly, and following through on support requests. Ensure that every interaction promotes confidence, satisfaction, and trust in IT services.
  • Maintain and Support Endpoint Devices: Set up, configure, and manage user laptops and peripherals remotely using tools like Intune. Monitor device performance and resolve issues related to configuration, updates, and system health.
  • Support Identity & Access Management: Manage user accounts, permissions, and access rights through Okta and Azure Active Directory. Handle onboarding and offboarding tasks, application assignments, group memberships, and MFA enrollments using Okta.
  • Assist with Patch Management & Security Compliance: Support patch deployment and compliance reporting through Intune and Microsoft 365 tools. Collaborate with IT leadership to enforce endpoint protection standards including encryption, antivirus, and device compliance policies.
  • Monitor and Respond to System Health Alerts: Proactively monitor system and endpoint alerts. Troubleshoot and resolve warnings related to patch status, disk encryption, VPN usage, and other security controls.
  • Contribute to IT Documentation: Create and maintain accurate, user-friendly documentation for internal systems, procedures, and support knowledge base articles. Ensure consistency in troubleshooting approaches and IT service delivery.
  • Support IT Projects and Rollouts: Assist with company-wide initiatives such as software upgrades, platform transitions, and security tool rollouts. Participate in testing, deployment, and user communication efforts.
  • Drive End-User Experience Improvements: Gather feedback from employees to identify recurring issues and areas for improvement. Work with IT leadership to recommend and implement solutions that enhance usability, reliability, and productivity.
  • Other duties as assigned

Ideal Candidate

  • Bachelor’s degree in information technology, Computer Science, or related field preferred.
  • 5 years of experience in IT support or a similar role, with a strong focus on providing exceptional customer service to internal users.
  • Proficiency in troubleshooting hardware, software, and network issues, with a proven ability to deliver timely resolutions.
  • Experience with installing, configuring, and maintaining desktop operating systems and software applications.
  • Strong knowledge of user account management, permissions, and access rights in Azure Directory and other IT systems.
  • Excellent communication and interpersonal skills, with a customer-centric approach to IT support.
  • Ability to work effectively both independently and collaboratively in a fast-paced environment.
  • Relevant certifications (e.g., CompTIA A+, Microsoft Certified Professional) are a plus.

What We Offer
• Opportunity to work in a fast-paced, highly dynamic environment where you help shape the culture of our young company, wear multiple hats, and learn quickly.
• Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits.

• Unlimited PTO

• Two, one-week company-wide shutdowns each year.
• Commitment to growing you professionally and providing access to resources to further your development.
• 100% remote with frequent all team, in-person meetings to build relationships and problem solve.

The expected salary range offer for this role is $95,000 to $110,000. Actual pay offered may vary depending on job related knowledge, experience, education, and geographic location.

As an equal opportunity employer, Spyre is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job-related characteristics or other prohibited grounds specified in applicable federal, state and local laws. We also embrace differences in experience and background, and welcome diversity of opinions and thought with active recruitment designed to create a stronger and better Spyre that is focused on developing life-changing products for patients.

Spyre Therapeutics, along with other biotech companies, has become aware of a surge in email scams targeting prospective job candidates within our industry. Please be aware that official recruiters at Spyre Therapeutics only use email addresses with the domain “@spyre.com.” We want to also emphasize that we never request candidates to make any purchases or divulge sensitive personal information via email.

Please also be aware that all job postings will be listed on our website at spyre.com/careers/.

Please ensure that you regularly check the email address that you provide during the application process for any updates from potential employers. Your application status, interview invitations, or job offers will be sent via email. Respond promptly to maintain your candidacy.